Elsewhere on the opening weekend, Manchester United host Leicester City, Liverpool entertain West Ham, and Championship winners Wolverhampton Wanderers welcome Everton to Molineux. The Gunners then visit Chelsea at Stamford Bridge a week later.
The Red Devils boss, who has managed in England for the majority of his career so far, believes the Three Lions can lift the World Cup this year due to the strength of the Premier League, where most of their players ply their trade.
Dates for all 380 matches will be revealed, with the league campaign running from 11 August to 19 May.
Manchester United starts at home to Leicester and plays only one of last season's top six, Tottenham, in its first eight games.
Following the Arsenal game, City do not face another top-six team until they are away to Liverpool - who beat Pep Guardiola's men in the quarter-finals of the Champions League last season - in October.
Trump, Kim meet for historic summit in Singapore
A White House read-out of Trump's meetings with Prime Minister Lee Hsien Loong today did not include mention of a state visit. His aides were on Twitter during the journey.0008 And Kim Jong Un is on his way now too.
Guardiola will look to retain the Premier League title for the first time since Manchester United in 2008/09.
Chelsea, who remain in a state of flux with question marks over their owner, manager and star players, have been handed a low-key start to the season, aside from the early meeting with Arsenal.
Fulham begin with London derbies against Crystal Palace and Tottenham, while Cardiff follow their opener at Bournemouth with a home game against Newcastle.
Woman goes viral after getting head stuck in exhaust pipe
Video posted to Facebook shows the woman sitting on the ground as emergency services attempt to free her. The local fire department was called in, and used a power saw to help get her out.
Arsenal will have home advantage during their first north London derby of the season with Mauricio Pochettino's men before travelling to the new White Hart Lane at the beginning of March.
Tesla Roadster 'SpaceX' package to get rocket thrusters?
The arrival of "full self-driving" features doesn't mean that Tesla cars will offer a complete autonomous driving experience. Troubled electric-car maker Tesla may be set to deliver new, fully autonomous vehicle features later this summer.