When Mourinho was Chelsea boss, Wenger shoved his rival on the Stamford Bridge touchline in 2014 after being on the wrong end of a 2-0 scoreline. After the Europa League match with Atletico Madrid tonight, he'll take on his greatest arch-nemesis, Jose Mourinho in league action.
Few stadiums have been more significant to Wenger than Old Trafford. Man United is a massive club with fantastic players. The Portuguese manager said he knew that building United back into an European powerhouse would take time.
Wenger will likely rotate his squad for this one, as his focus is now squarely on winning the Europa League trophy, and securing Champions League qualification for next season.
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The conference will also try to re-energise the floundering UN-led peace process in the hope of ending the war, which is now in its eighth year.
On Friday Mourinho said many of his antics should be seen in the context of trying to challenge Arsenal's position as England's leading team.
"(Dennis) Bergkamp, Thierry (Henry), (Sol) Campbell - incredible team.
There was Arsène Wenger, perching on a ledge having been sent to the Old Trafford stands, surrounded by jeering Manchester United supporters, holding his arms spread wide as though he had just been pulled away from a pub brawl.
"They pushed us to the limit, the two matches we played, not at the Emirates (Stadium), but at the fantastic old stadium (Highbury), unforgettable. We have a good relationship and we keep our individual memories".
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"We needed that, a bit more experience, mental aggressiveness".
Alexis Sanchez will face Arsenal for the first time since quitting the club to join United in January.
And, with the chance to get their hands on another piece of silverware in the FA Cup final on May 19, Mourinho is content with what he has achieved so far.
After 22 years with the Gunners, Wenger will depart at the end of the season. It is the place where one of the great rivalries of British football was established - between two giants of the game who would go on to become firm friends.
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The Prime Minister is now exclusively focused on internal party management and masking the divisions within her government. She was asked whether she would personally vote to keep Britain in the customs union if she was a backbench MP.