US President Donald Trump announced the airstrikes in retaliation for Syrian President Bashar Assad's alleged use of chemical weapons.
"We are not looking for a confrontation and refuse any logic of escalation", said Parly.
Following the announcement, the United States said strikes had been launched at 9pm EST (2am BST) and had destroyed important infrastructure at three sites connected to the Syrian regime's chemical weapons programme.
President Trump declared "mission accomplished" Saturday after US military forces carried out missile strikes with Britain and France against Syrian chemical-weapons facilities. "Clearly the Assad regime did not get the message past year", Mattis said.
But the USA, United Kingdom and France all expressed confidence that chlorine gas and a nerve agent were used in the April 7 attack, and that Assad's forces were behind it.
Trump said that the "massacre" last weekend in Syria "was a significant escalation in a pattern of chemical weapons use by that very bad regime".
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The Russian military also claimed Syria shot down the cruise missiles that were launched at a Syrian air base.
Russian lawmaker Vladimir Dzhabarov said on Saturday that Russia was likely to call for a meeting of the United Nations Security Council.
"The attack took place after the colonial forces supporting terrorists realized they have lost control got the feeling that they have lost credibility in front of their people and the world", Assad said.
"We did not do any coordination with Russian Federation on these strikes, and neither did we pre-notify them", Marine General Joseph Dunford, the chairman of the Joint Chiefs of Staff, said Friday night. "The American President, the French President and the British Prime Minister are criminals, they will gain nothing from it".
The attack came hours after US President Donald Trump confirmed he'd organised a strike on Damascus.
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"Insulting the president of Russian Federation is unacceptable and inadmissible", Antonov added.
Trump chastised Syria's two main allies, Russia and Iran, for their roles in supporting "murderous dictators", and noted that Russian President Vladimir Putin had guaranteed a 2013 global agreement for Assad to get rid of all of his chemical weapons.
He criticized Russia's support of the Syrian regime saying "Russia must decide if it will continue down this dark path".
"We can not tolerate the normalisation of the use of chemical weapons, which is a direct threat to the security of the Syrian people and our collective security", Macron said.
Among the more bombastic tweets was that of U.S. Senator Lindsey Graham who wrote, "We should apply "3 strikes, you're out" to the butcher of Damascus".
Trump also called out Russia's promise in 2013 that they would guarantee the elimination of Syria's chemical weapons.
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