More than 86 percent of sample specimens tested in the state for Influenza A - the most rampant flu strain plaguing Texas this year - tested positive, according to the CDC's latest report.
Last week, the health department reported 22 flu-associated deaths.
According to the health department's latest report on Thursday, 45 people, including three in Oklahoma County, have died due to the flu since September 1, 2017.
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Experts say that 288 people had to be hospitalized within the last week due to the flu virus, bringing the total number of hospitalizations to 1,141. The Ashtabula County Health Department said the person was over 65 years old.
The number of flu outbreaks in long-term care facilities in Douglas County jumped from 14 to 16 overnight.
The Oakland County Health Division strongly urges residents to get vaccinated against flu in the wake of increasing flu cases. The four who died all had underlying illnesses.
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Symptoms include fever or chills, cough, sore throat, runny or stuffy nose, muscle or body aches, headaches and tiredness.
You can get a flu shot at many drugstores, retail stores, the Cuyahoga County Board of Health and doctors' offices.
The Health Division recommends everyone over the age of six months receive an influenza vaccination and take preventive actions.
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"We are now in the midst of a very active flu season with widespread and intense flu activity".