Keane, who was sold to Burnley by former Manchester United manager Louis van Gaal for just £2m, had an outstanding campaign with the Clarets last season and was handed his England debut against Germany in Dortmund in March.
And that left Everton essentially in a one-horse race for Keane, although Burnley were always prepared to hold onto the player for another season, even with him able to leave on a free transfer in the summer of 2018.
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Keane and Pickford were both nominated for the Professional Footballers' Association Young Player Of The Year award in 2017, which was won by Tottenham midfielder Dele Alli.
If that deal goes ahead, as it nearly certainly will, then United stand to see a healthy injection of cash to their bank as, according to the Burnley Express, they are entitled to 25 per cent of the player's transfer fee, having included a sell-on clause in the centre-half's contract when he left Old Trafford in 2015.
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And while they have paid £7m on Eupen striker Henry Onyekuru, Belgium's top scorer last season, they have loaned him to Anderlecht for a season.
Keane's expected arrival will not be the end of Everton's big spending, with manager Koeman determined to test Swansea City's resolve to keep 27-year-old Iceland midfielder Gylfi Sigurdsson.
Ever thought about the Oscar Meyer going for an entire Wienerfleet?!
Let's be frank, we knew it was only a matter of time before a drone was created exclusively for the goal of delivering hot dogs . The fully automatic WienerCycle, meanwhile, seats two (plus eight hot dogs), and boasts 8.5 horsepower and 80 mpg.